Bivalirudin Started during Emergency Transport for Primary PCI

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Bivalirudin started during emergency transport for primary PCI.

BACKGROUND Bivalirudin, as compared with heparin and glycoprotein IIb/IIIa inhibitors, has been shown to reduce rates of bleeding and death in patients undergoing primary percutaneous coronary intervention (PCI). Whether these benefits persist in contemporary practice characterized by prehospital initiation of treatment, optional use of glycoprotein IIb/IIIa inhibitors and novel P2Y12 inhibitor...

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BACKGROUND Treatment with the direct thrombin inhibitor bivalirudin, as compared with heparin plus glycoprotein IIb/IIIa inhibitors, results in similar suppression of ischemia while reducing hemorrhagic complications in patients with stable angina and non-ST-segment elevation acute coronary syndromes who are undergoing percutaneous coronary intervention (PCI). The safety and efficacy of bivalir...

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Transradial Access and Bivalirudin Combination for Reducing Post-PCI Bleeding

Bleeding is the most common complication after percutaneous coronary intervention (PCI) and has been shown to be a very significant adverse prognostic event, increasing short-term and longterm adverse outcomes. Access-site bleeding accounts for the majority of these hemorrhagic complications. Transradial access is associated with a very sizeable reduction in access-site-related bleeding. Patien...

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["Unsuitable for PCI..." Multivessel primary PCI. But for whom?].

Following the recent publication of the PRAMI trial, the appearance of the article entitled ‘‘Multivessel approach in ST-elevation myocardial infarction: Impact on in-hospital morbidity and mortality’’ by Santos et al. in this issue of the Journal could not be more timely. The study analyzed a population of patients with ST-elevation myocardial infarction (STEMI) included in the Portuguese Regi...

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ژورنال

عنوان ژورنال: New England Journal of Medicine

سال: 2013

ISSN: 0028-4793,1533-4406

DOI: 10.1056/nejmoa1311096